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Concept.png SSRI 
A class of drugs licensed to treat depression, increasingly used also for other health concerns.

Selective serotonin reuptake inhibitors (SSRIs) are a type of pharmaceutical which affects neurotransmitters (i.e. brain chemistry). They are widely prescribed, in the USA especially, to treat depression. Popular brand names include Prozac, Zoloft, Celexa and Lexapro.


In the United States, SSRIs are increasingly prescribed for a range of health concerns. Perhaps 25-60% of SSRI prescriptions are for drug dependence, "ADHD", anxiety disorders, autism (in children), bipolar disorder, eating disorders, fibromyalgia, neuropathic pain, obsessive-compulsive disorder and premenstrual dysphoric disorder. The clinical affect of other health conditions is a subject of ongoing research.[1]


SSRIs have a complex and not well-understood impact on people, with a wide range of responses. SSRI use is correlated with the rate of convicted offenses from assault to murder[2][3] as well as with suicide.[4] A lot of circumstantial evidence connects cases of gun violence, especially school shootings, to SSRI use.[5]

Many mass shooters have taken SSRIs.[6]


An example

Page nameDescription
FluvoxamineAn antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It may be of use in treating long Covid.


Related Quotation

David McGowan“If ignorance is truly bliss, then why do so many Americans need Prozac?”David McGowan2000