Hydroxychloroquine

Hydroxychloroquine  (drug)
Start	1938
Abbreviation	HCQ
Interest of	• Rick Bright • Marilyn Gladu • Craig Kelly • Martin Landray • Peter McCullough • Karen Whitsett • Zev Zelenko
A generic drug widely used to treat COVID-19, generally safe, with potential to significantly reduce the case fatality rate. In 2020 the subject of scientific papers of dubious repute that allege the contrary. Also subject to legal restrictions.

Hydroxychloroquine (HCQ) is a drug on the WHO's List of Essential Medicines, the safest and most effective medicines needed in a health system. In 2017, it was the 128^th most commonly prescribed medication in the US with more than five million prescriptions. In 2020 it was increasingly widely used to treat COVID-19. In an event termed "LancetGate", on 22 May 2020 the The Lancet published a study which highlighted risks of using the drug to treat COVID-19 only to retract it on the 5 June, an apparent part of a systematic campaign to undermine its usage. The WHO also cancelled some trials of the drug, citing safety concerns.

COVID-19

Hydroxychloroquine (HCQ) has been used worldwide to treat COVID-19. and was found to significantly lower the disease's case fatality rate, especially when given early on. Yale epidemiologist Harvey Risch has been an ardent supporter of its use, claiming that the drug is being suppressed by the commercially-controlled media and by Anthony Fauci.

Safety

Hydroxychloroquine has more than five million prescriptions per year. The treatment of COVID-19 cases with HCQ in the early stages was reported to have a major positive effect on outcomes. Shortly thereafter concerns were raised about its safety and trials were stopped. High doses of the drug can lead to ventricular fibrillation and eventually cardiac arrest, which however is well known and documented, so any prescription (initial dose or accumulative) that exceeded the limit caused the death of a patient deliberately, see "Price" further below.

Lancetgate

The Lancet ^[When?] "published a report that HCQ caused 35% more deaths due to adverse effects of the drug in another trial". By late May 2020 "140 academics and clinicians around the world have challenged the veracity of that Lancet article". The Lancet withdrew the paper after within 13 days was discovered to have been published by a shell company. The RECOVERY study in the UK also suggested it was dangerous, but involved very high doses that exceeded its dose for other illnesses.

On 4 July 2020, the WHO discontinued a trial involving hydroxychloroquine and lopinavir/ritonavir for hopitalized patients, citing safety concerns.

On 17 June 2020 the WHO stopped a trial on HCQ concluding that "there was no reduction in mortality’ with the drug", but without publishing any data. On the same day, the UK Recovery trial (funded in part by the Bill & Melinda Gates Foundation) was also stopped, reaching the same conclusion.

Legal status

In a 23 March 2020 executive order, the Governor of New York, Andrew Cuomo, barred pharmacists from filling prescriptions for chloroquine or hydroxychloroquine as part of clinical trials for COVID-19. In early April 2020 Anthony Fauci opposed the use of either drug as a treatment for severe cases of COVID-19, instead recommending the experimental (and considerably more expensive) remdesivir. By August 2020, with a lot of data showing the effectiveness of hydroxychloroquine, Jim Hoft was calling for Fauci's arrest.

Challenge

In June 2020 the Association of American Physicians and Surgeons filed a lawsuit against Department of Health and Human Services and the FDA for their “irrational interference” to hydroxychloroquine for treatment of patients.

Senators Ron Johnson, Ted Cruz and Mike Lee sent a letter to FDA Commissioner Stephen Hahn explicitly asking about the agency’s handling of information regarding hydroxychloroquine and its use to treat COVID-19.

Price

Compared to many drugs used to treat COVID-19 (remdesivir in particular)), HCQ is extremely cheap, inviting speculation that a media smear campaign was undertaken by the pharmaceutical industry -- like with ivermectin -- to impugn its safety. At the same time studies were set up that deliberately exceeded the known lethal dose for the drug.

 

Related Quotations

Page	Quote	Author	Date
"COVID-19/Vaccine"	“A vaccine is at least a year away, and success is uncertain. Treatments that hold promise need to be evaluated rigorously.”	World Bank/Human Development Practice Group
COVID-19/Censorship	“He Craig Kelly needs to decide what is the appropriate thing for a member of Parliament to be commenting on.”	Paul Kelly	January 2021
Ivermectin	“I want to bring attention to two critical deficits in our national treatment response that has made this hearing necessary in the first place. Besides the early interest and research into hydroxychloroquine, we can find no other significant efforts to research the use of any other already existing, safe, low-cost therapeutic agents. Seemingly the only research and treatment focus that we have observed on a national scale is with novel or high-cost pharmaceutically engineered products”	Dr. Pierre Kory	December 2020
Christian Perronne	“The problem with all the drug [regulatory] agencies in the world—the FDA in the United States, the European Medical Agency, the French drug agency—they all say “No, hydroxychloroquine doesn’t work; azithromycin doesn’t work; ivermectin doesn’t work,” despite many, many published proofs that they work. Because if they acknowledge that they do work, it’s impossible for them to market their so-called “vaccines”. That’s the only reason; it’s a marketing reason.”	Christian Perronne	13 August 2021
Karen Whitsett	“If President Trump had not talked about this, it would not be something that's accessible for anyone to be able to get that right now, it would not even be possible”	Karen Whitsett	2020

Many thanks to our Patrons who cover ~2/3 of our hosting bill. Please join them if you can.