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|( 1820s: ) 1821|
Napoleon Bonaparte dies in British captivity on Saint Helena, possibly of arsenic poisoning
- March 4 – James Monroe begins his second term as President of the United States.
- May 5 – Emperor Napoleon dies in exile on Saint Helena of stomach cancer.
- May 5 – The first edition of the Manchester Guardian newspaper (from 1959 simply The Guardian) is published in England.
- June 24 – Battle of Carabobo: Simón Bolívar wins Venezuela's independence from Spain
- July 19 - George IV is crowned king of the United Kingdom of Great Britain and Ireland.
- July 28 - Argentine general José de San Martín declares the independence of Peru from the Spanish Empire.
- September 15 - Guatemala, El Salvador, Honduras, Nicaragua and Costa Rica gain independence from Spain by the Act of Independence of Central America. On October 29, the newly independent First Mexican Empire proposes that Guatemala should merge with it.
- November 28 – Panama declares independence from Spain, joining Gran Colombia.
- December 1 – The Dominican Republic declares independence from Spain (see History of the Dominican Republic). It would be invaded by Haiti in 1822.
- December 15 – The world's first geographical society, the Société de géographie, is established in Paris.
|University of Buenos Aires|
|Title||Born||Place of birth||Died||Summary|
|Marcus Goldman||9 December 1821||Germany|
|20 July 1904||Financier|