Difference between revisions of "Iatrogenesis"

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<i>This article is an import from Wikipedia, and does not cover the [[Big Pharma]] aspect sufficently</i>
 
 
{{concept
 
{{concept
 
|wikipedia=https://en.wikipedia.org/wiki/Iatrogenesis
 
|wikipedia=https://en.wikipedia.org/wiki/Iatrogenesis
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|image_caption=Ancient Greek painting in a vase, showing a physician (''iatros'') bleeding a patient
 
|image_caption=Ancient Greek painting in a vase, showing a physician (''iatros'') bleeding a patient
 
|interest_of=Big Pharma,Ivan Illich
 
|interest_of=Big Pharma,Ivan Illich
|description=When the cure is worse than the illness.
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|description=When the cure is worse than the illness. [[ON]] says the medical system is the ''third'' leading cause of death in the US, while it might in fact be the ''leading''.
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|constitutes=Medical concept
 
|constitutes=Medical concept
 
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'''Iatrogenesis''' is the causation of a disease, a harmful complication, or other ill effect by any medical activity, including diagnosis, intervention, error, or negligence.<ref>https://www.merriam-webster.com/dictionary/iatrogenic</ref><ref>John O. Barr & Timothy L. Kauffman, "Iatrogenesis in older adults", in Timothy L. Kauffman, Ron Scott, John O. Barr & Michael L. Moran, eds., ''A Comprehensive Guide to Geriatric Rehabilitation'', 3rd edn. (Edinburgh: [[Churchill Livingstone]]/[[Elsevier]], 2014)</ref> First used in this sense in 1924,<ref>https://www.merriam-webster.com/dictionary/iatrogenic</ref> the term was introduced to [[Sociology of medicine|sociology]] in 1976 by [[Ivan Illich]], alleging that industrialized societies impair quality of life by [[Overmedicalization|overmedicalizing]] life.<ref name=":1">[https://www.encyclopedia.com/social-sciences/dictionaries-thesauruses-pictures-and-press-releases/iatrogenesis "iatrogenesis"], ''A Dictionary of Sociology'', [[Encyclopedia.com]]. updated 31 May 2020.</ref> Some iatrogenic events are obvious, like amputation of the wrong limb, whereas others, like drug interactions, can evade recognition. In a 2013 estimate, about 20&nbsp;million negative effects from treatment had occurred globally.<ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561509</ref>
  
'''Iatrogenesis''' is the causation of a disease, a harmful complication, or other ill effect by any medical activity, including diagnosis, intervention, error, or negligence.<ref>https://www.merriam-webster.com/dictionary/iatrogenic</ref><ref>John O. Barr & Timothy L. Kauffman, "Iatrogenesis in older adults", in Timothy L. Kauffman, Ron Scott, John O. Barr & Michael L. Moran, eds., ''A Comprehensive Guide to Geriatric Rehabilitation'', 3rd edn. (Edinburgh: [[Churchill Livingstone]]/[[Elsevier]], 2014)</ref> First used in this sense in 1924,<ref>https://www.merriam-webster.com/dictionary/iatrogenic</ref> the term was introduced to [[Sociology of medicine|sociology]] in 1976 by [[Ivan Illich]], alleging that industrialized societies impair quality of life by [[Overmedicalization|overmedicalizing]] life.<ref>name=":1">[https://www.encyclopedia.com/social-sciences/dictionaries-thesauruses-pictures-and-press-releases/iatrogenesis "iatrogenesis"], ''A Dictionary of Sociology'', [[Encyclopedia.com]]. updated 31 May 2020.</ref> Iatrogenesis may thus include mental suffering via medical beliefs or a practitioner's statements.<ref>https://www.encyclopedia.com/social-sciences/dictionaries-thesauruses-pictures-and-press-releases/iatrogenesis</ref><ref>David Kuhl, ''What Dying People Want: Practical Wisdom for the End of Life'' (New York: [[PublicAffairs]], 2002), [https://books.google.com/books?id=QfiLuC7a47sC&pg=PA55&dq=iatrogenic+suffering p 55].</ref><ref>Paul F. Lazarsfeld, "Working with Merton", in Lewis A. Cosar, ed., ''The Idea of Social Structure: Papers in Honor of [[Robert K. Merton]]'' (New Brunswick, NJ: [[Transaction Publishers]], 2012 / New York: [[Harcourt, Brace, Jovanovich|Harcourt Brace Jovanovich]], 1975), [https://books.google.com/books?id=ByFhcDveoK0C&q=iatrogenesis indexing "iatrogenesis"], esp. pp 328–329.</ref> Some iatrogenic events are obvious, like amputation of the wrong limb, whereas others, like drug interactions, can evade recognition. In a 2013 estimate, about 20&nbsp;million negative effects from treatment had occurred globally.<ref>cite journal|last1=Global Burden of Disease Study 2013|first1=Collaborators|date=22 August 2015|title=Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013.|journal=Lancet|volume=386|issue=9995|pages=743–800|doi=10.1016/s0140-6736(15)60692-4|pmc=4561509|pmid=26063472</ref>
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While the [[medical industry]] will admit that it is the ''third'' leading cause of death<ref>https://www.cnbc.com/2018/02/22/medical-errors-third-leading-cause-of-death-in-america.html</ref>, it might in fact be the ''leading'', even ahead of [[heart disease]] and [[cancer]].<ref>https://anh-usa.org/is-medicine-really-the-third-leading-cause-of-death-in-the-us/</ref>
 
 
According to the [[World Health Organization]] (WHO) for 2019, millions of patients are injured and 2.6 million people die each year as a result of non-compliance with safety regulations in health care<ref>https://www.who.int/ru/news-room/detail/13-09-2019-who-calls-for-urgent-action-to-reduce-patient-harm-in-healthcare</ref>.
 
 
 
==Iatrogenic avenues==
 
 
 
===[[Complication (medicine)|Risk]] associated with medical interventions===
 
*[[Adverse effect]]s of prescription drugs
 
* Overuse of drugs (causing, for example, [[antibiotic resistance]] in [[bacteria]])
 
* Prescription [[drug interaction]]
 
 
 
=== [[Medical error]]s ===
 
* Incorrect [[Medical prescription|prescription]], perhaps due to illegible [[handwriting]] or computer [[typos]]
 
* Faulty procedures, techniques, information, methods, or equipment
 
* [[Negligence]]
 
* [[Hospital-acquired infection]]s
 
 
 
==Causes and consequences==
 
 
 
===Medical error and negligence===
 
 
 
Iatrogenic conditions do not necessarily result from [[medical error]]s, such as mistakes made in [[surgery]], or the prescription or dispensing of the wrong therapy, such as a [[Medication|drug]]. In fact, intrinsic and sometimes [[adverse effect (medicine)|adverse effects]] of a medical treatment are iatrogenic. For example, [[radiation therapy]] and [[chemotherapy]] — necessarily aggressive for therapeutic effect – frequently produce such iatrogenic effects as [[hair loss]], [[hemolytic anemia]], [[diabetes insipidus]], [[vomiting]], [[nausea]], [[brain damage]], [[lymphedema]], infertility, etc. The loss of function resulting from the required removal of a diseased organ is iatrogenic, as in the case of [[diabetes]] consequential to the removal of all or part of the [[pancreas]].
 
 
 
The incidence of iatrogenesis may be misleading in some cases. For example, ruptured [[aortic aneurysm]] is fatal in most cases; the survival rate for a ruptured aortic aneurysm is under 25%. Patients who die during or after an operation will still be considered iatrogenic deaths, but the procedure itself remains a better bet than the 100% probability of death if left untreated.
 
 
 
Other situations may involve actual [[negligence]] or faulty procedures, such as when [[Pharmacotherapy|pharmacotherapist]]s produce handwritten prescriptions for drugs.
 
 
 
===Adverse effects===
 
 
 
A very common iatrogenic effect is caused by [[drug interaction]], i.e., when pharmacotherapists fail to check for all medications a patient is taking and prescribe new ones that interact agonistically or antagonistically (thereby potentiating or attenuating the intended therapeutic effect). Such situations can cause significant [[morbidity]] and [[death|mortality]]. Adverse reactions, such as [[allergy|allergic reactions]] to drugs, even when unexpected by pharmacotherapists, are also classified as iatrogenic.
 
 
 
The evolution of [[antibiotic resistance]] in [[bacteria]] is iatrogenic as well.<ref>Cite journal|author=Finland M |title=Emergence of antibiotic resistance in hospitals, 1935–1975 |journal=Rev. Infect. Dis. |volume=1 |issue=1 |pages=4–22 |year=1979 |pmid=45521|doi=10.1093/clinids/1.1.4 </ref> Bacterial strains resistant to antibiotics have evolved in response to the overprescription of [[antibiotic]] drugs.<ref>name="Llor Bjerrum pp. 229–241">cite journal | last1=Llor | first1=Carl | last2=Bjerrum | first2=Lars | title=Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem | journal=Therapeutic Advances in Drug Safety | publisher=SAGE Publications | volume=5 | issue=6 | date=16 October 2014 | issn=2042-0986 | doi=10.1177/2042098614554919 | pmid=25436105 | pages=229–241| pmc=4232501 </ref>
 
 
 
Certain drugs are toxic in their own right in therapeutic doses because of their mechanism of action. [[Alkylating antineoplastic agent]]s, for example, cause [[DNA damage]], which is more harmful to cancer cells than regular cells. However, [[alkylation]] causes severe side-effects and is actually [[carcinogenic]] in its own right, with potential to lead to the development of secondary tumors. In a similar manner, [[arsenic]]-based medications like [[melarsoprol]], used to treat [[trypanosomiasis]], can cause [[arsenic poisoning]].
 
 
 
Adverse effects can appear mechanically. The design of some surgical instruments may be decades old, hence certain adverse effects (such as tissue trauma) may never have been properly characterized.
 
 
 
===Psychiatry===
 
 
 
In psychiatry, iatrogenesis can occur due to [[Medical error|misdiagnosis]] (including diagnosis with a false condition, as was the case of [[hystero-epilepsy]]<ref>Spanos, Nicholas P. |title=Multiple Identities & False Memories: A Sociocognitive Perspective |publisher=American Psychological Association (APA) |year=1996 |isbn=1-55798-340-2 </ref>). An example of a partially iatrogenic condition due to common misdiagnosis is [[bipolar disorder]], especially in pediatric patients.<ref>John R Pruett Jr, Joan L. Luby http://www.medscape.com/viewarticle/466375_print </ref> Other conditions such as [[somatoform disorder]] and [[chronic fatigue syndrome]] are theorized to have significant sociocultural and iatrogenic components.<ref>Abbey, S.E. | year = 1993 | title = Somatization, illness attribution and the sociocultural psychiatry of chronic fatigue syndrome | journal = Ciba Found Symp | volume = 173 | pages = 238–52 |pmid=8491101 | doi = 10.1002/9780470514382.ch14 | series = Novartis Foundation Symposia | isbn = 9780470514382 </ref> [[Posttraumatic stress disorder]] is hypothesized to be prone to iatrogenic complications based on treatment modality.<ref>Boscarino, JA | year =2004 | title = Evaluation of the Iatrogenic Effects of Studying Persons Recently Exposed to a Mass Urban Disaster | url = http://mailer.fsu.edu/~cfigley/IatrogenicEffectsfinal3p1.pdf | access-date =  4 May 2008 |archive-url = https://web.archive.org/web/20080625161528/http://mailer.fsu.edu/~cfigley/IatrogenicEffectsfinal3p1.pdf |archive-date = 25 June 2008</ref> Even use of antipsychotic drugs leads to loss of brain mass<ref>Ho|first1=Beng-Choon|last2=Andreasen|first2=Nancy C.|last3=Ziebell|first3=Steven|last4=Pierson|first4=Ronald|last5=Magnotta|first5=Vincent|date=February 2011|title=Long-term Antipsychotic Treatment and Brain Volumes|journal=Archives of General Psychiatry|volume=68|issue=2|pages=128–137|doi=10.1001/archgenpsychiatry.2010.199|issn=0003-990X|pmc=3476840|pmid=21300943</ref><ref>https://www.psychiatrictimes.com/antipsychotics-and-shrinking-brain</ref>
 
 
 
The psychiatric treatment of some conditions and populations, such as [[substance abuse]],<ref>Moos, R.H. | year = 2005 | title = Iatrogenic effects of psychosocial interventions for substance use disorders: prevalence, predictors, prevention | journal = Addiction | volume = 100 | issue = 5 | pages = 595–604 | doi = 10.1111/j.1360-0443.2005.01073.x | pmid = 15847616</ref> and antisocial youths<ref>Weiss, B. |author2=Caron, A. |author3=Ball, S. |author4=Tapp, J. |author5=Johnson, M. |author6= Weisz, J.R.  | year = 2005 | title = Iatrogenic effects of group treatment for antisocial youths | journal = Journal of Consulting and Clinical Psychology | volume = 73 | issue = 6 | pages = 1036–1044 | url =http://eric.ed.gov:80/ERICWebPortal/custom/portlets/recordDetails/detailmini.jsp?_nfpb=true&_&ERICExtSearch_SearchValue_0=EJ734173&ERICExtSearch_SearchType_0=no&accno=EJ734173 | doi = 10.1037/0022-006X.73.6.1036 | pmid = 16392977| pmc = 4024049 </ref> are regarded as carrying significant risks for iatrogenesis. At the other end of the spectrum, [[dissociative identity disorder]] is considered by a minority of theorists to be a wholly iatrogenic disorder with the bulk of diagnoses arising from a tiny fraction of practitioners.<ref>Spanos, Nicholas P. |title=Multiple Identities & False Memories: A Sociocognitive Perspective |publisher=American Psychological Association (APA)</ref><ref>name=Braun1989>Cite journal| author = Braun, B.G. | year = 1989 | journal = Dissociation |volume=2 |issue=2 | title = Iatrophilia and Iatrophobia in the diagnosis and treatment of MPD (Morose Parasitic Dynamism)| pages =  43, 161–2, 165–6, 171–2 passim | hdl = 1794/1425 </ref>
 
 
 
The degree of association of any particular condition with iatrogenesis is unclear and in some cases controversial. The over-diagnosis of psychiatric conditions (with the assignment of mental illness terminology) may relate primarily to clinician dependence on subjective criteria.{{cn}} The assignment of pathological nomenclature is rarely a benign process and can easily rise to the level of emotional iatrogenesis, especially when no alternatives outside of the diagnostic naming process have been considered. Many former patients come to the conclusion that their difficulties are largely the result of the power relationships inherent in psychiatric treatment, which has led to the rise of the [[anti-psychiatry]] movement.{{cn}}
 
 
 
===Iatrogenic poverty===
 
 
 
Meessen et al. used the term "iatrogenic poverty" to describe impoverishment induced by medical care.<ref>Cite journal|author1=Meessen, B. |author2=Zhenzhong, Z. |author3=Van Damme, W. |author4=Devadasan, N. |author5=Criel, B. |author6=Bloom, G. |title= Iatrogenic poverty |journal= Tropical Medicine & International Health |volume=8 |issue=7 |pages=581–4 |year=2003  |doi=10.1046/j.1365-3156.2003.01081.x|pmid=12828538 |doi-access=free </ref> Impoverishment is described for households exposed to catastrophic health expenditure<ref>Cite journal|author= Xu |title= Protecting Households from Catastrophic Health Spending |journal= Health Affairs |volume=26 |issue=4 |pages=972–83 |year=2007 |pmid= 17630440|doi=10.1377/hlthaff.26.4.972 |last2= Evans |first2= DB |last3= Carrin |first3= G |last4= Aguilar-Rivera |first4= AM |last5= Musgrove |first5= P |last6= Evans |first6= T |display-authors=etal|doi-access= free </ref> or to hardship financing.<ref>Cite journal|author= Kruk |title= Borrowing And Selling To Pay For Health Care in Low- And Middle-Income Countries |journal= Health Affairs |volume=28 |issue=4 |pages=10056–66 |year=2009 |pmid= 19597204|doi=10.1377/hlthaff.28.4.1056 |last2= Goldmann |first2= E. |last3= Galea |first3= S.|display-authors=etal|url= https://deepblue.lib.umich.edu/bitstream/2027.42/63445/1/Kruk_Borrowing%20health%20care_2009.pdf |hdl= 2027.42/63445 </ref> Every year, worldwide, over 100,000 households fall into [[Poverty#Health care|poverty]] due to health care expenses. A study reported that in the United States in 2001, illness and [[medical debt]] caused half of all personal [[Bankruptcy in the United States|bankruptcies]].<ref>cite web|  url= http://www.consumeraffairs.com/news04/2005/bankruptcy_study.html | title= Medical Bills Leading Cause of Bankruptcy, Harvard Study Finds </ref> Especially in countries in [[Transition economy|economic transition]], the [[willingness to pay]] for [[health care]] is increasing, and the supply side does not stay behind and develops very fast. But the regulatory and protective capacity in those countries is often lagging behind. Patients easily fall into a vicious cycle of illness, ineffective therapies, consumption of savings, indebtedness, sale of productive assets, and eventually poverty.
 
 
 
===Social and cultural iatrogenesis===
 
  
The 20th-century social critic [[Ivan Illich]] broadened the concept of medical iatrogenesis in his 1974 book ''Medical Nemesis: The Expropriation of Health''<ref>Cite book|author=Illich, Ivan|title=Medical Nemesis: The Expropriation of Health|publisher=Calder & Boyars|location=London|year=1974|isbn=0-7145-1096-3|url-access=registration|url=https://archive.org/details/medicalnemesisex00illirich</ref> by defining it at three levels.
 
*First, clinical iatrogenesis is the injury done to patients by ineffective, unsafe, and erroneous treatments as described above. In this regard, he described the need for [[evidence-based medicine]] 20 years before the term was coined.<ref>Cite journal|last=Pearce |first=Wright |s2cid=6678368 |year=2003 |title=Obituary: Ivan Illich |journal=The Lancet |volume=361 |issue=9352 |pages=185 |doi=10.1016/S0140-6736(03)12233-7 </ref>
 
*Second, at another level social iatrogenesis is the [[medicalization]] of life in which medical professionals, pharmaceutical companies, and medical device companies have a vested interest in sponsoring sickness by creating unrealistic health demands that require more treatments or treating non-diseases that are part of the normal human experience, such as age-related declines. In this way, aspects of medical practice and medical industries can produce social harm in which society members ultimately become less healthy or excessively dependent on institutional care. He argued that medical education of physicians contributes to medicalization of society because they are trained predominantly for diagnosing and treating illness, therefore they focus on disease rather than on health. Iatrogenic poverty (above) can be considered a specific manifestation of social iatrogenesis.
 
*Third, cultural iatrogenesis refers to the destruction of traditional ways of dealing with, and making sense of, death, suffering, and sickness. In this way the medicalization of life leads to cultural harm as society members lose their autonomous coping skills. It is worth noting that in these critiques "Illich does not reject all benefits of modern society but rejects those that involve unwarranted dependency and exploitation."<ref>Cite journal|last=Barnet |first=Robert |year=2003 |title=Ivan Illich and the Nemesis of Medicine |journal=Medicine, Health Care and Philosophy |volume=6 |issue=3 |pages=273–286 |pmid=14620464 |doi=10.1023/a:1025991708888</ref>
 
  
==Number of Cases==
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==Official narrative==
 
According to the [[World Health Organization]] (WHO) for [[2019]], millions of patients are injured and 2.6 million people die each year in low- and middle-income countries as a result of non-compliance with safety regulations in health care. Around the world, the personal, social and economic harm caused by harm to patients amounts to many trillions of US dollars. According to the WHO Director General Dr. [[TA Gebreyesus]], every minute in the world at least one person dies from harm in the provision of medical care<ref>https://www.who.int/ru/news-room/detail/13-09-2019-who-calls-for-urgent-action-to-reduce-patient-harm-in-healthcare</ref>.
 
According to the [[World Health Organization]] (WHO) for [[2019]], millions of patients are injured and 2.6 million people die each year in low- and middle-income countries as a result of non-compliance with safety regulations in health care. Around the world, the personal, social and economic harm caused by harm to patients amounts to many trillions of US dollars. According to the WHO Director General Dr. [[TA Gebreyesus]], every minute in the world at least one person dies from harm in the provision of medical care<ref>https://www.who.int/ru/news-room/detail/13-09-2019-who-calls-for-urgent-action-to-reduce-patient-harm-in-healthcare</ref>.
  
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===USA===
 
===USA===
Based on these figures, iatrogenesis may cause as many as 225,000 deaths per year in the United States (excluding recognizable error). An earlier [[Institute of Medicine]] report estimated 230,000 to 284,000 iatrogenic deaths annually.<ref>https://web.archive.org/web/20101224104818/http://www.avaresearch.com/ava-main-website/files/20100401061256.pdf?page=files%2F20100401061256.pdf</ref> The US numbers include:
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Iatrogenesis may cause as many as 225,000 deaths per year in the United States (excluding recognizable error). An earlier [[Institute of Medicine]] report estimated 230,000 to 284,000 iatrogenic deaths annually.{{when}}<ref>https://web.archive.org/web/20101224104818/http://www.avaresearch.com/ava-main-website/files/20100401061256.pdf?page=files%2F20100401061256.pdf</ref> The US numbers include:
  
 
* 12,000 due to unnecessary surgery
 
* 12,000 due to unnecessary surgery
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[[Frederick van Pelt]], a doctor who works for [[The Chartis Group]], a health care consultancy, said another element of harm that is often overlooked is the number of severe patient injuries resulting from medical error. "Some estimates would put this number at 40 times the death rate," van Pelt said,<ref>https://www.washingtonpost.com/news/to-your-health/wp/2016/05/03/researchers-medical-errors-now-third-leading-cause-of-death-in-united-states/</ref> which means 10 million severe injuries as a result of medical errors.
 
[[Frederick van Pelt]], a doctor who works for [[The Chartis Group]], a health care consultancy, said another element of harm that is often overlooked is the number of severe patient injuries resulting from medical error. "Some estimates would put this number at 40 times the death rate," van Pelt said,<ref>https://www.washingtonpost.com/news/to-your-health/wp/2016/05/03/researchers-medical-errors-now-third-leading-cause-of-death-in-united-states/</ref> which means 10 million severe injuries as a result of medical errors.
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Dr. [[Gary Null]], a leading advocate of natural healing, calculated in his book ''Death by Medicine'' that conventional medicine is actually the number one cause of death in the US, killing 783,936 a year. Even this number may be an underestimate, since Null uses the [[Institute of Medicine]]'s number for hospital deaths caused by medical errors, when these more recent calculations put it much higher.<ref>https://anh-usa.org/is-medicine-really-the-third-leading-cause-of-death-in-the-us/</ref>
  
 
===Germany===
 
===Germany===
 
In [[Germany]], only one third of all errors that occur in the regulation of medicines are the responsibility of the nursing staff, where confusion, for example, played a role here. In the other two thirds of cases, it is the doctors who are responsible, for example due to non-observance of contraindications or negative interactions. According to calculations, 57,000 people die at Internal Medicine stations every year due to medical drugs. Of these, 28,000 deaths are avoidable<ref>Krisengebiet Krankenhaus. In: Stern. Nr. 36, 2010, S. 34 ff.</ref>.
 
In [[Germany]], only one third of all errors that occur in the regulation of medicines are the responsibility of the nursing staff, where confusion, for example, played a role here. In the other two thirds of cases, it is the doctors who are responsible, for example due to non-observance of contraindications or negative interactions. According to calculations, 57,000 people die at Internal Medicine stations every year due to medical drugs. Of these, 28,000 deaths are avoidable<ref>Krisengebiet Krankenhaus. In: Stern. Nr. 36, 2010, S. 34 ff.</ref>.
  
==History==
 
[[File:Yearly mortality rates 1784-1849.png|thumb|upright=1.3|Evidence demonstrating the advent of [[pathological anatomy]] in 1823 Vienna (left vertical line) correlated with incidence of fatal childbed fever. The onset of chlorine handwash in 1847 is noted (right vertical line). For comparison, rates for Dublin maternity hospital, which had no pathological anatomy ([[Historical mortality rates of puerperal fever#Yearly mortality rates for birthgiving women 1784–1849|view rates]]). [[Ignaz Semmelweis|Semmelweis]] 1861.]]
 
  
The term [[wikt:en:iatrogenesis#English|iatrogenesis]] means ''brought forth by a healer'', from the [[Greek language|Greek]] [[wikt:en:ἰατρός#Ancient Greek|ἰατρός]] (''iatros'', "healer") and [[wikt:en:γένεσις#Ancient Greek|γένεσις]] (''genesis'', "origin"); as such, in its earlier forms, it could refer to good or bad effects.
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{{SMWQ
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|authors=Celia Farber
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|date=10 September 2021
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|text=The death blow to [[FDA]]'s safety function was AZT. After that, any potentially deadly disease became an excuse for curtailing clinical trials. [[Death by medication]] was normalized as an inherent part of progress.
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|source_name=The Real Anthony Fauci
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|subjects=iatrogenesis, FDA, AZT
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}}
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==Covid-19==
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Many of the responses to [[Covid-19]] were iatrogenic.
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Regardless of what one thinks of the actual existence, origins or severity of [[Covid-19]], it is clear the early treatments methods caused severe damage. The treatment protocols, like in Italy in March 2020, demanded hospitals use a mix of strong [[antibiotics]] and mechanical ventilators. Even in routine circumstances, people put on respirators have a high risk severe complications or dying<ref>https://www.evms.edu/covid-19/covid_care_for_clinicians/</ref>. The heavy-duty antibiotics, in themselves severely weakening patients, were even more counterproductive in a hospital environment where antibiotic-resistant bacteria were common<ref>https://vimeo.com/404203138</ref>.  
  
Since at least the time of [[Hippocrates]], people have recognized the potentially damaging effects of medical intervention. "First do no harm" (''[[primum non nocere]]'') is a primary Hippocratic mandate in modern [[bioethics|medical ethics]]. Iatrogenic illness or death caused purposefully or by avoidable error or negligence on the healer's part became a punishable offense in many civilizations.<ref>cite book |title=Organization Development in Healthcare: Conversations on Research and Strategies |editor=Jason A Wolf |editor2=Heather Hanson |editor3=Mark J Moir |editor4=Len Friedman |editor5=Grant T Savage |date=12 July 2011 |publisher=Emerald Group Pub |isbn=978-0-85724-709-4 |page=292 |series=Advances in Health Care Management Series #10</ref>
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*The closing of hospitals led to delayed or cancelled medical treatment for other problems like cancer, heart disease,surgical procedures and many others <ref>https://collateralglobal.org/physical-health</ref>.
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*General societal health and well-being is neglected.
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*The enforced isolation of elderly people, stated as a measure protect them, led to widespread depression and loss of will to live<ref>https://collateralglobal.org/dementia</ref>.
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*The general societal climate of fear has caused widespread psychological sufferings like depression,suicidal thoughts<ref>https://collateralglobal.org/suicide</ref>, obsessive-compulsive behavior like excessive hand-washing<ref>https://www.scientificamerican.com/article/covid-19-worsens-obsessive-compulsive-disorder-but-therapy-offers-coping-skills1/</ref> or other hygiene measures, self-isolation or needless fear of death.
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*The enforced mask-wearing will increase the risk of number<ref>https://www.who.int/publications/i/item/advice-on-the-use-of-masks-in-the-community-during-home-care-and-in-healthcare-settings-in-the-context-of-the-novel-coronavirus-(2019-ncov)-outbreak</ref> of illnesses, from bacterial infections<ref>https://bmjopen.bmj.com/content/5/4/e006577</ref>, rotten teeth ('mask mouth'), carbon dioxide poisoning<ref>https://corona-transition.org/zweites-kind-wegen-maskentragen-gestorben</ref><ref>https://www.thatsmags.com/china/post/31100/student-deaths-lead-schools-to-adjust-rules-on-masks-while-exercising</ref><ref>https://swprs.org/face-masks-evidence/</ref>, to increased long term health risks{{cn}}.
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*The [[Covid-19/Vaccine|insufficiently tested vaccines]] being pushed on people 2021 out are likely to cause an unknown amount of health damage.
  
The transfer of pathogens from the autopsy room to maternity patients, leading to shocking [[historical mortality rates of puerperal fever]] (also known as "childbed fever") at maternity institutions in the 19th century, was a major iatrogenic catastrophe of the era. The infection mechanism was first identified by [[Ignaz Semmelweis]].<ref>cite journal|last=Hanninen|first=O|author2=Farago, M. |author3=Monos, E. |title=Ignaz Philipp Semmelweis, the prophet of bacteriology|journal=Infection Control and Hospital Epidemiology|year=1983|volume=4|issue=5|pages=367–370|pmid=6354955|jstor=30142576|doi=10.1017/S0195941700059762 </ref>
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==Vaccines==
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{{FA|Vaccines}}
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A 1977 study published in ''[[The Lancet]]'' stated that the risks of the whole-cell pertussis jab (used in the DTP [[vaccine]]) exceeded the risks associated with wild pertussis.<ref>https://doi.org/10.1016/S0140-6736(77)91028-5</ref>
  
With the development of [[scientific medicine]] in the 20th century, it could be expected that iatrogenic illness or death might be more easily avoided. [[Antiseptic]]s, [[anesthesia]], [[antibiotic]]s, better surgical techniques, [[evidence based medicine|evidence-based]] [[Guideline (medical)|protocols]] and [[best practices]] continue to be developed to decrease iatrogenic side effects and [[death|mortality]].
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In 1983 an [[NIH]]-funded [[UCLA]] study found that Wyeth's DTP vaccine was killing or causing severe brain injury, including seizures
 +
and death, in 1 in every 300 vaccinated children.<ref>http://scihub.se/10.1097/00006454-198301000-00003</ref> The resultant lawsuits
 +
caused the collapse of insurance markets for vaccines and threatened to bankrupt the industry. Wyeth—now Pfizer—claimed to be losing $20 in
 +
downstream liability for every dollar it earned on vaccine sales, and induced Congress to pass the National Childhood Vaccine Injury Act in
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1986 shielding vaccine makers from liability.<ref>http://congress.gov/bill/99th-congress/house-bill/5546</ref>
 +
 
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==Ivan Illich: The Expropriation of Health==
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The 20th-century social critic [[Ivan Illich]] broadened the concept of medical iatrogenesis in his 1974 book ''Medical Nemesis: The Expropriation of Health''<ref> Ivan Illich <i>Medical Nemesis: The Expropriation of Health</i> isbn=0-7145-1096-3 https://archive.org/details/medicalnemesisex00illirich</ref> by defining it at three levels.
 +
*First, clinical iatrogenesis is the injury done to patients by ineffective, unsafe, and erroneous treatments as described above. In this regard, he described the need for [[evidence-based medicine]] 20 years before the term was coined.<ref>Pearce, Wright (2003). "Obituary: Ivan Illich". The Lancet. 361 (9352): 185 |doi=10.1016/S0140-6736(03)12233-7 </ref>
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*Second, at another level social iatrogenesis is the [[medicalization]] of life in which medical professionals, pharmaceutical companies, and medical device companies have a vested interest in sponsoring sickness by creating unrealistic health demands that require more treatments or treating non-diseases that are part of the normal human experience, such as age-related declines. In this way, aspects of medical practice and medical industries can produce social harm in which society members ultimately become less healthy or excessively dependent on institutional care. He argued that medical education of physicians contributes to medicalization of society because they are trained predominantly for diagnosing and treating illness, therefore they focus on disease rather than on health. Iatrogenic poverty (above) can be considered a specific manifestation of social iatrogenesis.
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*Third, cultural iatrogenesis refers to the destruction of traditional ways of dealing with, and making sense of, death, suffering, and sickness. In this way the medicalization of life leads to cultural harm as society members lose their autonomous coping skills. It is worth noting that in these critiques "Illich does not reject all benefits of modern society but rejects those that involve unwarranted dependency and exploitation."<ref>Barnet, Robert (2003). "Ivan Illich and the Nemesis of Medicine". Medicine, Health Care and Philosophy. 6 (3): 273–286 |doi=10.1023/a:1025991708888</ref>
  
  

Latest revision as of 02:57, 10 September 2023

Concept.png Iatrogenesis 
(Medical concept)Rdf-entity.pngRdf-icon.png
Iatros.jpg
Ancient Greek painting in a vase, showing a physician (iatros) bleeding a patient
Interest of• Ivan Illich
• Robert Mendelsohn
When the cure is worse than the illness. ON says the medical system is the third leading cause of death in the US, while it might in fact be the leading.

Iatrogenesis is the causation of a disease, a harmful complication, or other ill effect by any medical activity, including diagnosis, intervention, error, or negligence.[1][2] First used in this sense in 1924,[3] the term was introduced to sociology in 1976 by Ivan Illich, alleging that industrialized societies impair quality of life by overmedicalizing life.[4] Some iatrogenic events are obvious, like amputation of the wrong limb, whereas others, like drug interactions, can evade recognition. In a 2013 estimate, about 20 million negative effects from treatment had occurred globally.[5]

While the medical industry will admit that it is the third leading cause of death[6], it might in fact be the leading, even ahead of heart disease and cancer.[7]


Official narrative

According to the World Health Organization (WHO) for 2019, millions of patients are injured and 2.6 million people die each year in low- and middle-income countries as a result of non-compliance with safety regulations in health care. Around the world, the personal, social and economic harm caused by harm to patients amounts to many trillions of US dollars. According to the WHO Director General Dr. TA Gebreyesus, every minute in the world at least one person dies from harm in the provision of medical care[8].

The most serious consequences are caused by errors in diagnosis, in the prescription of medicines and their use. Medicinal errors alone cause an estimated US $42 billion annually in damage. Every year, non-observance of safety and hygiene rules during surgery causes complications in almost 25% of patients and leads to the death of one million patients during surgery or immediately after it[9].

USA

Iatrogenesis may cause as many as 225,000 deaths per year in the United States (excluding recognizable error). An earlier Institute of Medicine report estimated 230,000 to 284,000 iatrogenic deaths annually.[When?][10] The US numbers include:

  • 12,000 due to unnecessary surgery
  • 7,000 due to medication errors in hospitals
  • 20,000 due to other errors in hospitals
  • 80,000 due to nosocomial infections in hospitals
  • 106,000 due to non-error, negative effects of drugs

A study 2016 from the Johns Hopkins University School of Medicine calculated 251,000 deaths per year, equating to nearly 700 deaths a day, about 9.5 percent of all deaths annually in the United States.[11]

Dr. Martin Makary, the leader of the study, said “Moreover, the Centers for Disease Control and Prevention doesn’t require reporting of errors in the data it collects about deaths through billing codes, making it hard to see what’s going on at the national level.”

Frederick van Pelt, a doctor who works for The Chartis Group, a health care consultancy, said another element of harm that is often overlooked is the number of severe patient injuries resulting from medical error. "Some estimates would put this number at 40 times the death rate," van Pelt said,[12] which means 10 million severe injuries as a result of medical errors.

Dr. Gary Null, a leading advocate of natural healing, calculated in his book Death by Medicine that conventional medicine is actually the number one cause of death in the US, killing 783,936 a year. Even this number may be an underestimate, since Null uses the Institute of Medicine's number for hospital deaths caused by medical errors, when these more recent calculations put it much higher.[13]

Germany

In Germany, only one third of all errors that occur in the regulation of medicines are the responsibility of the nursing staff, where confusion, for example, played a role here. In the other two thirds of cases, it is the doctors who are responsible, for example due to non-observance of contraindications or negative interactions. According to calculations, 57,000 people die at Internal Medicine stations every year due to medical drugs. Of these, 28,000 deaths are avoidable[14].


“The death blow to FDA's safety function was AZT. After that, any potentially deadly disease became an excuse for curtailing clinical trials. Death by medication was normalized as an inherent part of progress.”
Celia Farber (10 September 2021)  [15]

Covid-19

Many of the responses to Covid-19 were iatrogenic.

Regardless of what one thinks of the actual existence, origins or severity of Covid-19, it is clear the early treatments methods caused severe damage. The treatment protocols, like in Italy in March 2020, demanded hospitals use a mix of strong antibiotics and mechanical ventilators. Even in routine circumstances, people put on respirators have a high risk severe complications or dying[16]. The heavy-duty antibiotics, in themselves severely weakening patients, were even more counterproductive in a hospital environment where antibiotic-resistant bacteria were common[17].

  • The closing of hospitals led to delayed or cancelled medical treatment for other problems like cancer, heart disease,surgical procedures and many others [18].
  • General societal health and well-being is neglected.
  • The enforced isolation of elderly people, stated as a measure protect them, led to widespread depression and loss of will to live[19].
  • The general societal climate of fear has caused widespread psychological sufferings like depression,suicidal thoughts[20], obsessive-compulsive behavior like excessive hand-washing[21] or other hygiene measures, self-isolation or needless fear of death.
  • The enforced mask-wearing will increase the risk of number[22] of illnesses, from bacterial infections[23], rotten teeth ('mask mouth'), carbon dioxide poisoning[24][25][26], to increased long term health risks[citation needed].
  • The insufficiently tested vaccines being pushed on people 2021 out are likely to cause an unknown amount of health damage.

Vaccines

Full article: Vaccines

A 1977 study published in The Lancet stated that the risks of the whole-cell pertussis jab (used in the DTP vaccine) exceeded the risks associated with wild pertussis.[27]

In 1983 an NIH-funded UCLA study found that Wyeth's DTP vaccine was killing or causing severe brain injury, including seizures and death, in 1 in every 300 vaccinated children.[28] The resultant lawsuits caused the collapse of insurance markets for vaccines and threatened to bankrupt the industry. Wyeth—now Pfizer—claimed to be losing $20 in downstream liability for every dollar it earned on vaccine sales, and induced Congress to pass the National Childhood Vaccine Injury Act in 1986 shielding vaccine makers from liability.[29]

Ivan Illich: The Expropriation of Health

The 20th-century social critic Ivan Illich broadened the concept of medical iatrogenesis in his 1974 book Medical Nemesis: The Expropriation of Health[30] by defining it at three levels.

  • First, clinical iatrogenesis is the injury done to patients by ineffective, unsafe, and erroneous treatments as described above. In this regard, he described the need for evidence-based medicine 20 years before the term was coined.[31]
  • Second, at another level social iatrogenesis is the medicalization of life in which medical professionals, pharmaceutical companies, and medical device companies have a vested interest in sponsoring sickness by creating unrealistic health demands that require more treatments or treating non-diseases that are part of the normal human experience, such as age-related declines. In this way, aspects of medical practice and medical industries can produce social harm in which society members ultimately become less healthy or excessively dependent on institutional care. He argued that medical education of physicians contributes to medicalization of society because they are trained predominantly for diagnosing and treating illness, therefore they focus on disease rather than on health. Iatrogenic poverty (above) can be considered a specific manifestation of social iatrogenesis.
  • Third, cultural iatrogenesis refers to the destruction of traditional ways of dealing with, and making sense of, death, suffering, and sickness. In this way the medicalization of life leads to cultural harm as society members lose their autonomous coping skills. It is worth noting that in these critiques "Illich does not reject all benefits of modern society but rejects those that involve unwarranted dependency and exploitation."[32]



 

An example

Page nameDescription
COVID-19/Medical killingsDuring the COVID-19 deep event, a number of governments implemented policies that drastically increased death numbers

 

A Iatrogenesis victim on Wikispooks

TitleDescription
Evert VermeerDutch journalist turned politician who attended the 1958 Bilderberg. Fell ill in 1959 and died in 1960

 

Related Quotation

PageQuoteAuthorDate
Michael Yeadon“Government’s response to emergencies is guided by the scientific group who sit together under the Scientific Advisory Group for Emergencies or SAGE. So they should provide scientific advice to the government about what’s appropriate to do. SAGE has got several things wrong, and that has led to advice that’s inappropriate and – uh, not only has had horrible economic effects, but has had continuing medical effects in that people are no longer being treated properly.”Michael YeadonNovember 2020
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References

  1. https://www.merriam-webster.com/dictionary/iatrogenic
  2. John O. Barr & Timothy L. Kauffman, "Iatrogenesis in older adults", in Timothy L. Kauffman, Ron Scott, John O. Barr & Michael L. Moran, eds., A Comprehensive Guide to Geriatric Rehabilitation, 3rd edn. (Edinburgh: Churchill Livingstone/Elsevier, 2014)
  3. https://www.merriam-webster.com/dictionary/iatrogenic
  4. "iatrogenesis", A Dictionary of Sociology, Encyclopedia.com. updated 31 May 2020.
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561509
  6. https://www.cnbc.com/2018/02/22/medical-errors-third-leading-cause-of-death-in-america.html
  7. https://anh-usa.org/is-medicine-really-the-third-leading-cause-of-death-in-the-us/
  8. https://www.who.int/ru/news-room/detail/13-09-2019-who-calls-for-urgent-action-to-reduce-patient-harm-in-healthcare
  9. https://www.who.int/ru/news-room/detail/13-09-2019-who-calls-for-urgent-action-to-reduce-patient-harm-in-healthcare
  10. https://web.archive.org/web/20101224104818/http://www.avaresearch.com/ava-main-website/files/20100401061256.pdf?page=files%2F20100401061256.pdf
  11. http://www.bmj.com/content/353/bmj.i2139
  12. https://www.washingtonpost.com/news/to-your-health/wp/2016/05/03/researchers-medical-errors-now-third-leading-cause-of-death-in-united-states/
  13. https://anh-usa.org/is-medicine-really-the-third-leading-cause-of-death-in-the-us/
  14. Krisengebiet Krankenhaus. In: Stern. Nr. 36, 2010, S. 34 ff.
  15. The Real Anthony Fauci
  16. https://www.evms.edu/covid-19/covid_care_for_clinicians/
  17. https://vimeo.com/404203138
  18. https://collateralglobal.org/physical-health
  19. https://collateralglobal.org/dementia
  20. https://collateralglobal.org/suicide
  21. https://www.scientificamerican.com/article/covid-19-worsens-obsessive-compulsive-disorder-but-therapy-offers-coping-skills1/
  22. https://www.who.int/publications/i/item/advice-on-the-use-of-masks-in-the-community-during-home-care-and-in-healthcare-settings-in-the-context-of-the-novel-coronavirus-(2019-ncov)-outbreak
  23. https://bmjopen.bmj.com/content/5/4/e006577
  24. https://corona-transition.org/zweites-kind-wegen-maskentragen-gestorben
  25. https://www.thatsmags.com/china/post/31100/student-deaths-lead-schools-to-adjust-rules-on-masks-while-exercising
  26. https://swprs.org/face-masks-evidence/
  27. https://doi.org/10.1016/S0140-6736(77)91028-5
  28. http://scihub.se/10.1097/00006454-198301000-00003
  29. http://congress.gov/bill/99th-congress/house-bill/5546
  30. Ivan Illich Medical Nemesis: The Expropriation of Health isbn=0-7145-1096-3 https://archive.org/details/medicalnemesisex00illirich
  31. Pearce, Wright (2003). "Obituary: Ivan Illich". The Lancet. 361 (9352): 185 |doi=10.1016/S0140-6736(03)12233-7
  32. Barnet, Robert (2003). "Ivan Illich and the Nemesis of Medicine". Medicine, Health Care and Philosophy. 6 (3): 273–286 |doi=10.1023/a:1025991708888
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