Immunocontraception

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Concept.png Immunocontraception 
(Contraception,  Population control,  Population reduction,  Vaccine)Rdf-entity.pngRdf-icon.png
Immunocontraception is the use of vaccines in order to cause temporary infertility.

Immunocontraception involves the administration of a vaccine that induces an adaptive immune response which causes temporary infertility.

The techniques are anything but new. Contraceptive vaccines have been used in numerous settings. Human experiments abound.

An extensive overview on human research dating back to the 1970s and now (2021) being approved in India can be found on https://en.wikipedia.org/w/index.php?title=Immunocontraception&oldid=1042082027

Antisperm contraceptive vaccines

There is even a peer reviewed journal dedicated solely to the subject of Immunocontraception. The American Journal of Reproductive Immunology, states in a paper called Antisperm contraceptive vaccines: where we are and where we are going?:

   "The population growth and unintended pregnancies are major public health issues worldwide."
   "almost any antibody/immunoglobulin can affect sperm function and fertilization to some degree"
   "Their contraceptive effect in vivo is being investigated."  
   "There is variability of immune response among individuals after any vaccination." (first sentence in section Passive Immunocontraceptive)
   "Even injection of Freund’s adjuvant alone, especially the complete, without any sperm antigen can cause some degree of antifertility effect"
   "This work has been supported over the years by funds from the NIH and several other agencies."(emph. added)[1]

The lab headed by Rajesh K. Naz which is one of the very few doing in vivo studies: Robert C. Byrd Health Sciences Center North, West Virginia University, School of Medicine, Room 2085, 1 Medical Center Drive, Morgantown, WV 26506-9186, USA.

A vaccine that prevents pregnancy in women

Research begun in the 1970s led to clinical trials in humans of a human chorionic gonadotropin (hCG) birth control vaccine. A phase I (safety) clinical trial examined 15 women from clinics in Helsinki, Finland, Uppsala, Sweden, Bahia, Brazil, and Santiago, Chile with a vaccine formed by conjugating the beta subunit of hCG with a tetanus toxoid. In plain English: a abortion agent was mixed into a tetanus vaccine, tried clinically and then administered to unwitting African women.

The administration of hCG necessitates use of a carrier and as carriers both tetanus vaccines and diphtheria vaccines were used in combination. This more potent version of the combined vaccine was used in a phase II (efficacy) trial during 1991-1993 conducted at 3 locations: the All India Institute of Medical Sciences, Safdarjung Hospital in New Delhi, and the Post Graduate Institute of Medical Education and Research in Chandigarh. Primary immunization consisted of 3 injections at 6 week intervals. The efficacy was rated 80%.[2]


 

Related Quotation

PageQuoteAuthorDate
Bill Gates“First, we've got population. The world today has 6.8 billion people. That's headed up to about nine billion. Now, if we do a really great job on new vaccines, health care, reproductive health services, we could lower that by, perhaps, 10 or 15 percent.”Bill Gates
Innovating to zero TED talk
18 February 2010


References

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110624/
  2. Talwar, GP; OM Singh; R Pal; N Chatterjee; P Sahai; K Dhall; J Kaur; SK Das; S Suri; K Buckshee; L Saraya; BN Saxena (1994). "A vaccine that prevents pregnancy in women". Proc Natl Acad Sci USA. 91 (18): 8532–8536. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC44640/


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