Centre for Evidence-Based Medicine
 CEBM (Oxford University)     | |
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The Centre for Evidence-Based Medicine (CEBM) based in the Nuffield Department of Primary Care Health Sciences in the University of Oxford is an academic-led centre dedicated to the practice, teaching and dissemination of high quality evidence-based medicine to improve healthcare in everyday clinical practice. CEBM was founded by David Sackett in 1995. It was subsequently directed by Brian Haynes and Paul Glasziou. Since 2010 it has been led by Professor Carl Heneghan, a Clinical Epidemiologist and General Practitioner.[1]
There are currently over 25 active staff and honorary members of the CEBM. Many of the active staff include other clinicians, statisticians, epidemiologists, information specialists, quantitative and qualitative researchers. Philosopher of Evidence-Based Medicine Jeremy Howick is a former fellow of the CEBM.
COVID-19 evidence service
| Prof. Carl Heneghan speaking in 2015 |
CEBM provides a COVID-19 evidence service which is updated daily as new information emerges. It sets out the current Case Fatality Rate (CFR) estimates, the country-specific issues affecting the CFR, and gives a current best estimate of the CFR, and more importantly, the Infection Fatality Rate (IFR).
The IFR estimates the fatality rate in all those with infection: the detected disease (cases) and those with an undetected disease (asymptomatic and not tested group).
The total number of cases and the total number of deaths from COVID-19 outbreak data was drawn down (scraped) from https://www.worldometers.info/coronavirus/ and the current best assumption, as of the 9th April 2020, is the CFR is 0.72% – the lowest end of the current prediction interval and in line with several other estimates.
Estimating CFR and IFR in the early stage of outbreaks is subject to considerable uncertainties, the estimates are likely to change as more data emerges.[2]
References
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