Prion diseases

Prion diseases  (disease)
Magnetic resonance image of sporadic CJD
All known prion diseases in mammals affect the structure of the brain or other neural tissue; all are progressive, have no known effective treatment, and are always fatal.

Prions are misfolded proteins with the ability to transmit their misfolded shape onto normal variants of the same protein. They characterize several fatal and transmissible neurodegenerative diseases in humans and many other animals. It is not known what causes the normal protein to misfold, but the abnormal three-dimensional structure is suspected of conferring infectious properties, collapsing nearby protein molecules into the same shape. The word prion derives from "proteinaceous infectious particle". The hypothesized role of a protein as an infectious agent stands in contrast to all other known infectious agents such as viroids, viruses, bacteria, fungi, and parasites, all of which contain nucleic acids (DNA, RNA, or both).

Prion isoforms of the prion protein (PrP), whose specific function is uncertain, are hypothesized as the cause of transmissible spongiform encephalopathies (TSEs), including scrapie in sheep, chronic wasting disease (CWD) in deer, bovine spongiform encephalopathy (BSE) in cattle (commonly known as "mad cow disease") and Creutzfeldt–Jakob disease (CJD) in humans. All known prion diseases in mammals affect the structure of the brain or other neural tissue; all are progressive, have no known effective treatment, and are always fatal.

Creutzfeldt-Jakob disease

Full article: Creutzfeldt-Jakob disease

In a strange coincidence, AstraZeneca senior vaccine researcher José Baselga was stated to have died of CJD.

COVID-19 vaccine

There have been reported incidences of people dying of this disease in connection with the COVID-vaccines. Neurological disorders are one of the main observed effects of the RNA vaccines. Immunologist J. Bart Classen published a paper in February 2021 outlining the potential for messenger RNA (mRNA) COVID vaccines to trigger development of prion diseases. These include Alzheimer’s, Parkinson’s, amyotrophic lateral sclerosis (ALS), multiple system atrophy (MSA) and others.

In November 2021, Nobel prizewinner Luc Montagnier warned about a connection between the mRNA vaccines and prion disease. “First we saw the common, immediate side effects (headaches, localized pain, fatigue, fever etc.) which, in general, do not last long. Then we saw, a few months later, numerous cardiovascular problems such as myocarditis in young people. Now we are seeing cases of prion disease such as Creutzfeld-Jakob disease, which is a fatal degenerative brain disorder.” In general, cases of Creutzfeld-Jakob disease are extremely rare. But already 7 cases of Creutzfeld-Jakob have been reported in France. Montagnier expressed surprise that C-J disease has appeared so early on in vaccine recipients.

Cheryl Cohen, a "healthy 64-year-old woman from Florida" died three months after her second dose of Pfizer’s COVID vaccine. According to her daughter, Gianni, she received the first dose of Pfizer on April 5, and her second dose on April 25. On May 6, Cheryl experienced her first episode indicating “something was neurologically wrong.” At first doctors couldn’t find anything medically wrong with Cheryl other than a slightly elevated white blood cell count But then MRI imaging of the brain showed evidence of prion disease, and on July 12 a second lumbar puncture came back positive for CJD. No autopsy was performed.

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References

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