Difference between revisions of "Creutzfeldt-Jakob disease"

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|description=A fatal degenerative brain disorder. Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances. Later symptoms include dementia, involuntary movements, blindness, weakness, and coma. About 70% of people die within a year of diagnosis.
 
|description=A fatal degenerative brain disorder. Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances. Later symptoms include dementia, involuntary movements, blindness, weakness, and coma. About 70% of people die within a year of diagnosis.
 
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'''Creutzfeldt–Jakob disease''' ('''CJD'''), also known as '''subacute spongiform encephalopathy''' or '''neurocognitive disorder due to prion disease''', is a fatal [[neurodegeneration|degenerative]] [[brain disorder]].<ref name=NIH2003/><ref name=CDC2015Main>https://www.cdc.gov/prions/cjd/index.html</ref> Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances.<ref name=NIH2003/> Later symptoms include [[dementia]], involuntary movements, blindness, weakness, and [[coma]].<ref name=NIH2003/> About 70% of people die within a year of diagnosis.<ref name=NIH2003/> The name Creutzfeldt–Jakob disease was introduced by [[Walther Spielmeyer]] in 1922, after the German neurologists [[Hans Gerhard Creutzfeldt]] and [[Alfons Maria Jakob]].<ref>http://www.whonamedit.com/synd.cfm/696.html Creutzfeldt–Jakob disease</ref>
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'''Creutzfeldt–Jakob disease''' ('''CJD'''), also known as '''subacute spongiform encephalopathy''' or '''neurocognitive disorder due to prion disease''', is a fatal [[neurodegeneration|degenerative]] [[brain disorder]].<ref name=NIH2003/><ref name=CDC2015Main>https://www.cdc.gov/prions/cjd/index.html</ref> Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances.<ref name=NIH2003/> Later symptoms include [[dementia]], involuntary movements, blindness, weakness, and [[coma]].<ref name=NIH2003/> About 70% of people die within a year of diagnosis.<ref name=NIH2003/>  
  
 
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There is no specific treatment for CJD.<ref name=NIH2003>https://web.archive.org/web/20170704234755/https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Creutzfeldt-Jakob-Disease-Fact-Sheet</ref> [[Opioids]] may be used to help with pain, while [[clonazepam]] or [[sodium valproate]] may help with involuntary movements.<ref name=NIH2003/> CJD affects about one per million people per year.<ref name=NIH2003/> Onset is typically around 60 years of age.<ref name=NIH2003/> The condition was first described in 1920.<ref name=NIH2003/> It is classified as a type of [[transmissible spongiform encephalopathy]].<ref>https://web.archive.org/web/20170808104028/https://www.cdc.gov/prions/cjd/about.html</ref> Inherited CJD accounts for about 10% of prion disease cases.<ref name=Man2015>https://doi.org/10.3171%2F2015.8.FOCUS15328</ref> Sporadic CJD is different from [[bovine spongiform encephalopathy]] (mad cow disease) and [[variant Creutzfeldt–Jakob disease]] (vCJD).<ref name=CDC2015Ind>https://web.archive.org/web/20170718154357/https://www.cdc.gov/prions/cjd/index.html|a</ref>
 
There is no specific treatment for CJD.<ref name=NIH2003>https://web.archive.org/web/20170704234755/https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Creutzfeldt-Jakob-Disease-Fact-Sheet</ref> [[Opioids]] may be used to help with pain, while [[clonazepam]] or [[sodium valproate]] may help with involuntary movements.<ref name=NIH2003/> CJD affects about one per million people per year.<ref name=NIH2003/> Onset is typically around 60 years of age.<ref name=NIH2003/> The condition was first described in 1920.<ref name=NIH2003/> It is classified as a type of [[transmissible spongiform encephalopathy]].<ref>https://web.archive.org/web/20170808104028/https://www.cdc.gov/prions/cjd/about.html</ref> Inherited CJD accounts for about 10% of prion disease cases.<ref name=Man2015>https://doi.org/10.3171%2F2015.8.FOCUS15328</ref> Sporadic CJD is different from [[bovine spongiform encephalopathy]] (mad cow disease) and [[variant Creutzfeldt–Jakob disease]] (vCJD).<ref name=CDC2015Ind>https://web.archive.org/web/20170718154357/https://www.cdc.gov/prions/cjd/index.html|a</ref>
  
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==COVID-19 vaccine==
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There have been reported incidences of people dying of this disease in connection with the [[COVID-vaccines]]. Neurological disorders are one of the main observed effects of the [[RNA vaccines]]. Immunologist [[J. Bart Classen]] published a paper in February 2021 outlining the potential for messenger RNA (mRNA) COVID vaccines to trigger development of prion diseases. These include [[Alzheimer’s]], [[Parkinson’s]], [[amyotrophic lateral sclerosis]] (ALS), [[multiple system atrophy]] (MSA) and others.<ref>https://childrenshealthdefense.org/defender/scientist-warning-covid-vaccines-parkinson-neurodegenerative-disorders/</ref>
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In a strange coincidence, [[AstraZeneca]] senior vaccine researcher [[José Baselga]] was stated to have died of CJD.
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Cheryl Cohen, a "healthy 64-year-old woman from [[Florida]]" died three months after her second dose of [[Pfizer–BioNTech COVID-19 vaccine|Pfizer’s COVID vaccine]]. According to her daughter, Gianni, she received the first dose of Pfizer on April 5, and her second dose on April 25. On May 6, Cheryl experienced her first episode indicating “something was neurologically wrong.” At first doctors couldn’t find anything medically wrong with Cheryl other than a slightly elevated white blood cell count But then MRI imaging of the brain showed evidence of prion disease, and on July 12 a second lumbar puncture came back positive for CJD. No autopsy was performed.<ref>https://childrenshealthdefense.org/defender/cheryl-cohen-dies-rare-brain-disease-second-dose-pfizer-covid-shot/?itm_term=home</reF>
  
 
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Revision as of 13:52, 2 September 2021

Concept.png Creutzfeldt-Jakob disease 
(disease)Rdf-entity.pngRdf-icon.png
Practneurol-2016-001571f02.jpg
Magnetic resonance image of sporadic CJD
A fatal degenerative brain disorder. Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances. Later symptoms include dementia, involuntary movements, blindness, weakness, and coma. About 70% of people die within a year of diagnosis.

Creutzfeldt–Jakob disease (CJD), also known as subacute spongiform encephalopathy or neurocognitive disorder due to prion disease, is a fatal degenerative brain disorder.[1][2] Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances.[1] Later symptoms include dementia, involuntary movements, blindness, weakness, and coma.[1] About 70% of people die within a year of diagnosis.[1]

CJD is caused by a type of abnormal protein known as a prion.[3] Infectious prions are misfolded proteins that can cause normally folded proteins to also become misfolded.[1] About 85% of cases of CJD occur for unknown reasons, while about 7.5% of cases are inherited from a person's parents in an autosomal dominant manner.[1] Exposure to brain or spinal tissue from an infected person may also result in spread.[1] There is no evidence that sporadic CJD can spread between people via normal contact or blood transfusions, although this is possible in variant Creutzfeldt–Jakob disease.[4] Diagnosis involves ruling out other potential causes.[1] An electroencephalogram, spinal tap, or magnetic resonance imaging may support the diagnosis.[1]

There is no specific treatment for CJD.[1] Opioids may be used to help with pain, while clonazepam or sodium valproate may help with involuntary movements.[1] CJD affects about one per million people per year.[1] Onset is typically around 60 years of age.[1] The condition was first described in 1920.[1] It is classified as a type of transmissible spongiform encephalopathy.[5] Inherited CJD accounts for about 10% of prion disease cases.[6] Sporadic CJD is different from bovine spongiform encephalopathy (mad cow disease) and variant Creutzfeldt–Jakob disease (vCJD).[7]

COVID-19 vaccine

There have been reported incidences of people dying of this disease in connection with the COVID-vaccines. Neurological disorders are one of the main observed effects of the RNA vaccines. Immunologist J. Bart Classen published a paper in February 2021 outlining the potential for messenger RNA (mRNA) COVID vaccines to trigger development of prion diseases. These include Alzheimer’s, Parkinson’s, amyotrophic lateral sclerosis (ALS), multiple system atrophy (MSA) and others.[8]

In a strange coincidence, AstraZeneca senior vaccine researcher José Baselga was stated to have died of CJD.

Cheryl Cohen, a "healthy 64-year-old woman from Florida" died three months after her second dose of Pfizer’s COVID vaccine. According to her daughter, Gianni, she received the first dose of Pfizer on April 5, and her second dose on April 25. On May 6, Cheryl experienced her first episode indicating “something was neurologically wrong.” At first doctors couldn’t find anything medically wrong with Cheryl other than a slightly elevated white blood cell count But then MRI imaging of the brain showed evidence of prion disease, and on July 12 a second lumbar puncture came back positive for CJD. No autopsy was performed.[9]


 

A Creutzfeldt-Jakob disease victim on Wikispooks

TitleDescription
José BaselgaChief cancer researcher at AstraZeneca dies at 61 of Creutzfeldt-Jakob disease, possibly an effect of the Covid jab.
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References

  1. ↑ a b c d e f g h i j k l m n https://web.archive.org/web/20170704234755/https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Creutzfeldt-Jakob-Disease-Fact-Sheet
  2. ↑ https://www.cdc.gov/prions/cjd/index.html
  3. ↑ https://www.cdc.gov/prions/cjd/index.html |website=www.cdc.gov
  4. ↑ https://www.transfusionguidelines.org/transfusion-handbook/5-adverse-effects-of-transfusion/5-4-variant-creutzfeldt-jakob-disease-vcjd
  5. ↑ https://web.archive.org/web/20170808104028/https://www.cdc.gov/prions/cjd/about.html
  6. ↑ https://doi.org/10.3171%2F2015.8.FOCUS15328
  7. ↑ https://web.archive.org/web/20170718154357/https://www.cdc.gov/prions/cjd/index.html%7Ca
  8. ↑ https://childrenshealthdefense.org/defender/scientist-warning-covid-vaccines-parkinson-neurodegenerative-disorders/
  9. ↑ https://childrenshealthdefense.org/defender/cheryl-cohen-dies-rare-brain-disease-second-dose-pfizer-covid-shot/?itm_term=home
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