Difference between revisions of "Thalidomide"

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'''Thalidomide''', sold as '''Contergan''' and '''Thalomid''' (among others), is a medication used to treat a number of cancers and other illnesses. It is an immunomodulatory medication and works by a number of mechanisms.
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'''Thalidomide''', sold as '''Contergan''' and '''Thalomid''' (among others), was a medication used to treat a number of cancers and other illnesses. It is an immunomodulatory medication and works by a number of mechanisms.
  
 
==Problems==
 
==Problems==
Contergan was marketed to women during pregnancy to help with anxiety, trouble sleeping, "tension", and morning sickness.<ref>https://books.google.de/books?id=LbHWgd-mDbsC&pg=PA644&redir_esc=y</ref> It lead to a high number of birth defects; the total number of embryos affected by use during pregnancy is estimated at 10,000, of which about 40% died around the time of birth.<ref>https://www.drugs.com/monograph/thalidomide.html</ref><ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298636/</ref>
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Contergan was marketed to women during pregnancy to help with anxiety, trouble sleeping, "tension", and morning sickness.<ref>https://books.google.de/books?id=LbHWgd-mDbsC&pg=PA644&redir_esc=y</ref> It lead to a high number of birth defects; the total number of embryos affected by use during pregnancy is estimated at 10,000, of which about 40% died around the time of birth.<ref>https://www.drugs.com/monograph/thalidomide.html</ref><ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298636/</ref> The medication was tested on children in Germany in a study up to [[1960]] (the drug was taken of the market in [[1961]].<ref>https://www.katholisch.de/artikel/26575-bericht-contergan-experimente-an-kindern-in-caritas-einrichtung</ref>
  
 
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Revision as of 23:56, 8 January 2022

Concept.png Thalidomide 
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Thalidomide, sold as Contergan and Thalomid (among others), was a medication used to treat a number of cancers and other illnesses. It is an immunomodulatory medication and works by a number of mechanisms.

Problems

Contergan was marketed to women during pregnancy to help with anxiety, trouble sleeping, "tension", and morning sickness.[1] It lead to a high number of birth defects; the total number of embryos affected by use during pregnancy is estimated at 10,000, of which about 40% died around the time of birth.[2][3] The medication was tested on children in Germany in a study up to 1960 (the drug was taken of the market in 1961.[4]


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